Mission
About Us

Mission

The goal of the new interdisciplinary research center is to harness the immense potential of optogenetics—the control of cellular activity using light and light-sensitive proteins (opsins)—for clinical medicine. Under the leadership of Prof. Dr. Tobias Moser, Director of the Institute for Auditory Neuroscience at the UMG, the center has been focusing since April 2024 on researching four novel therapeutic approaches targeting deafness, blindness, gastric paralysis, and motor deficits. The aim is to develop optogenetic cochlear implants, optogenetic therapies for vision restoration, gastric pacemakers, and brain-computer interfaces for future use in patients.

Development

Specifically, the EKFZ for Optogenetic Therapies aims at the development and implementation of four therapeutic approaches:
Team I: Optogenetic Hearing Restoration
Team II: Optogenetic Vision Restoration
Team III: Optogenetic Gastric Pacemaking
Team IV: Optogenetic Brain Computer Interfaces
These teams, with their expertise and the support of the five platforms, aim to develop therapeutic options for patients suffering from deafness, blindness, gastroparesis, or motor deficits. This includes the development of optogenetic cochlear implants and optogenetic tools for retinal stimulation, for gastric pacemakers, and brain-computer interfaces.

Forr all EKFZ forr Optogenetic Therapies
Prof. Dr. Tobias Moser (Spokesperson)
Prof. Dr. Emilie Macé (Deputy Spokesperson)
Prof. Dr. Dr. Tobias Brügmann (Deputy Spokesperson)

Implementation

The new optogenetic therapy procedure aims to develop an innovative method and bring it into clinical application within the next ten years.

Film about the Else Kröner Fresenius Center for Optogenetic Therapies (© EKFS)

Audiovisual Art Project Lets You Experience

“Hearing with Light”

Experience

Göttingen researchers, under the leadership of the University Medical Center Göttingen (UMG), have collaborated with audiologists and artists from film and music to translate the sound experience of an optogenetic cochlear implant into image and sound. The music video artistically conveys the restoration of “hearing with light”, a technology that promises an improved hearing experience compared to classical cochlear implants.

The award-winning video artist Boris Seewald directed the video, while the internationally renowned composer Ralf Hildenbeutel is responsible for the music. Together, they created a work that combines research, technology, and emotion in an intense visual and auditory experience. The video is hand-animated and comprises about 2,500 individual images. You can find a making-of under News & Events.

About us

The Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ) uses light to explore new paths in medicine. The goal is to make optogenetic methods – the targeted control of cells through light – usable for clinical application. Since April 2024, interdisciplinary teams led by Prof. Dr. Tobias Moser have been researching four innovative therapeutic approaches for deafness, blindness, gastroparesis, and motor deficits.

Besser Hören mit Licht