{"id":8299,"date":"2025-10-15T16:29:55","date_gmt":"2025-10-15T14:29:55","guid":{"rendered":"https:\/\/ekfz.uni-goettingen.de\/high-throughput-retinal-organoids-for-therapy-development\/"},"modified":"2026-02-03T11:24:27","modified_gmt":"2026-02-03T10:24:27","slug":"high-throughput-retinal-organoids-for-therapy-development","status":"publish","type":"post","link":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/","title":{"rendered":"High-throughput Retinal Organoids for Therapy Development"},"content":{"rendered":"

Dear Ladies and Gentlemen,<\/p>\n

We cordially invite you to the next EKFZ Guest Lecture:<\/p>\n

Dr. Magdalena Renner: High-throughput Retinal Organoids for Therapeutic Development<\/strong><\/p>\n

Date and time:
\nNovember 5, 2025, 4:00 PM<\/strong><\/p>\n

Location:
\nLecture hall of the DPZ (Kellnerweg 4, 37077 G\u00f6ttingen)<\/strong><\/p>\n

Abstract:
\nRetinal organoids are a 3D in vitro model of the human retina that models its cell type diversity, arrangement, transcriptome, and functional aspects. Although human retinal organoids require 30 weeks to mature, we have established methods to use them for high-content screening of adeno-associated viral vectors (AAV). Our goal is to identify regulatory elements that lead to AAV-driven gene expression exclusively in specific cell types of the human retina. Cell type-specific gene expression is important to minimize toxicity caused by off-target expression of gene therapy vectors. Furthermore, cell type-specific transgene expression provides access to specific cells for basic research in various model systems. Beyond the retina, the methods we have developed are broadly applicable across the entire field of organoid research: We use cost-effective laboratory automation for high-throughput organoid generation, maintenance, and screening, and have increased the throughput of organoid cryosectioning and histology with the HistoBrick array format. <\/p>\n

Prof. Dr. Emilie Mac\u00e9 will receive the speaker. If you would like to meet Magdalena Renner before the lecture, please contact Emilie by email (emilie.mace@med.uni-goettingen.de<\/a>). <\/p>\n

Please feel free to forward this announcement and information flyer to anyone who might be interested.<\/p>\n

Best regards,
\nMarie<\/p>\n

Download as PDF<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Dear Ladies and Gentlemen, We cordially invite you to the next EKFZ Guest Lecture: Dr. Magdalena Renner: High-throughput Retinal Organoids for Therapeutic…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[177],"tags":[],"class_list":["post-8299","post","type-post","status-publish","format-standard","hentry","category-older-lectures"],"acf":[],"yoast_head":"\nHigh-throughput Retinal Organoids for Therapy Development - ekfz<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High-throughput Retinal Organoids for Therapy Development - ekfz\" \/>\n<meta property=\"og:description\" content=\"Dear Ladies and Gentlemen, We cordially invite you to the next EKFZ Guest Lecture: Dr. Magdalena Renner: High-throughput Retinal Organoids for Therapeutic...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/\" \/>\n<meta property=\"og:site_name\" content=\"ekfz\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-15T14:29:55+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-03T10:24:27+00:00\" \/>\n<meta name=\"author\" content=\"Michael Riemann\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Michael Riemann\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/\",\"url\":\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/\",\"name\":\"High-throughput Retinal Organoids for Therapy Development - ekfz\",\"isPartOf\":{\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/#website\"},\"datePublished\":\"2025-10-15T14:29:55+00:00\",\"dateModified\":\"2026-02-03T10:24:27+00:00\",\"author\":{\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/ba5b4374d7100beb3905443d24464678\"},\"breadcrumb\":{\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\/\/ekfz.uni-goettingen.de\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"High-throughput Retinal Organoids for Therapy Development\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/#website\",\"url\":\"https:\/\/ekfz.uni-goettingen.de\/en\/\",\"name\":\"ekfz\",\"description\":\"Else Kr\u00f6ner Fresenius Zentrum f\u00fcr Optogenetische Therapien\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/ekfz.uni-goettingen.de\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/ba5b4374d7100beb3905443d24464678\",\"name\":\"Michael Riemann\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/fae6f483fef9e6003d67e19df8818461498f94c12899e5ea898c2d7d931de00e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/fae6f483fef9e6003d67e19df8818461498f94c12899e5ea898c2d7d931de00e?s=96&d=mm&r=g\",\"caption\":\"Michael Riemann\"},\"sameAs\":[\"https:\/\/www.basta.de\"],\"url\":\"https:\/\/ekfz.uni-goettingen.de\/en\/author\/micha\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"High-throughput Retinal Organoids for Therapy Development - ekfz","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/","og_locale":"en_US","og_type":"article","og_title":"High-throughput Retinal Organoids for Therapy Development - ekfz","og_description":"Dear Ladies and Gentlemen, We cordially invite you to the next EKFZ Guest Lecture: Dr. Magdalena Renner: High-throughput Retinal Organoids for Therapeutic...","og_url":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/","og_site_name":"ekfz","article_published_time":"2025-10-15T14:29:55+00:00","article_modified_time":"2026-02-03T10:24:27+00:00","author":"Michael Riemann","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Michael Riemann","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/","url":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/","name":"High-throughput Retinal Organoids for Therapy Development - ekfz","isPartOf":{"@id":"https:\/\/ekfz.uni-goettingen.de\/en\/#website"},"datePublished":"2025-10-15T14:29:55+00:00","dateModified":"2026-02-03T10:24:27+00:00","author":{"@id":"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/ba5b4374d7100beb3905443d24464678"},"breadcrumb":{"@id":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/ekfz.uni-goettingen.de\/en\/high-throughput-retinal-organoids-for-therapy-development\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/ekfz.uni-goettingen.de\/en\/"},{"@type":"ListItem","position":2,"name":"High-throughput Retinal Organoids for Therapy Development"}]},{"@type":"WebSite","@id":"https:\/\/ekfz.uni-goettingen.de\/en\/#website","url":"https:\/\/ekfz.uni-goettingen.de\/en\/","name":"ekfz","description":"Else Kr\u00f6ner Fresenius Zentrum f\u00fcr Optogenetische Therapien","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ekfz.uni-goettingen.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/ba5b4374d7100beb3905443d24464678","name":"Michael Riemann","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ekfz.uni-goettingen.de\/en\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/fae6f483fef9e6003d67e19df8818461498f94c12899e5ea898c2d7d931de00e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/fae6f483fef9e6003d67e19df8818461498f94c12899e5ea898c2d7d931de00e?s=96&d=mm&r=g","caption":"Michael Riemann"},"sameAs":["https:\/\/www.basta.de"],"url":"https:\/\/ekfz.uni-goettingen.de\/en\/author\/micha\/"}]}},"_links":{"self":[{"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/posts\/8299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/comments?post=8299"}],"version-history":[{"count":2,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/posts\/8299\/revisions"}],"predecessor-version":[{"id":9002,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/posts\/8299\/revisions\/9002"}],"wp:attachment":[{"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/media?parent=8299"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/categories?post=8299"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ekfz.uni-goettingen.de\/en\/wp-json\/wp\/v2\/tags?post=8299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}