{"id":6433,"date":"2025-02-13T08:48:11","date_gmt":"2025-02-13T07:48:11","guid":{"rendered":"https:\/\/ekfz.uni-goettingen.de\/publications\/"},"modified":"2026-03-04T12:04:46","modified_gmt":"2026-03-04T11:04:46","slug":"publications","status":"publish","type":"page","link":"https:\/\/ekfz.uni-goettingen.de\/en\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"
[vc_section][vc_row row_type=”main-section” stukram_section_layout=”section_grid”][vc_column][vc_empty_space height=”55px”][vc_column_text]\n

2026<\/span><\/h2>\n[\/vc_column_text][vc_column_text]
\n
\n 14. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Arousal elicits a brain-wide hemodynamic wave independent of locus coeruleus noradrenergic tone<\/h2>\n
\n

Martinez de Paz JM*, Mayer JL*, Wanken P, Rodrigues Apgaua B, Ablitip A, Behera L, Mac\u00e9 E. (2026) Arousal elicits a brain-wide hemodynamic wave independent of locus coeruleus noradrenergic tone. bioRxiv <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 14. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

A transition-prone brain state precedes spontaneous behavioral switching<\/h2>\n
\n

Wanken P, Edelman BJ, Behera L, Martinez de Paz JM, McCarthy PT, Mac\u00e9 E. (2026) A transition-prone brain state precedes spontaneous behavioral switching. bioRxiv <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 9. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Evaluation of Dysphagia in Myositis and Muscular Dystrophy Using Real-Time MRI and Quantitative Muscle Ultrasound<\/h2>\n
\n

Zeng R, Rietveld A, Al-Bourini O, Kroon RHMJM, Olthoff A, Weidenm\u00fcller M, Carstens PO, Kommerell I, Sch\u00fctz SG, Horlings CGC, Kalf JG, de Swart BJM, van Engelen BGM, Friede T, Hofer S, Frahm J, Seif Amir Hosseini A, Schmidt J, Saris CGJ (2026) Evaluation of Dysphagia in Myositis and Muscular Dystrophy Using Real-Time MRI and Quantitative Muscle Ultrasound. J Cachexia Sarcopenia Muscle <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 9. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Real-Time MRI With Deep Learning for Efficient Evaluation of Neuromuscular Breathing Impairment<\/h2>\n
\n

Zeng R, Al-Bourini O, Lettermann L, Lettermann L, Olgem\u00f6ller U, Hofer S, Boentert M, Friede T, Nietert M, Voit D, Frahm J, Uecker M, Seif Amir Hosseini A, Schmidt J. (2026) Real-Time MRI With Deep Learning for Efficient Evaluation of Neuromuscular Breathing Impairment. MedComm <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

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\n 7. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

How new therapies save our hearing<\/h2>\n
\n

Around 16 million people in Germany no longer hear well\u2014and the trend is rising. The good news: hearing technology is becoming ever more sophisticated. A new implant uses light signals to achieve what was previously impossible. <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 7. April 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Generation of marmoset monkeys with a non-mosaic disruption of the OTOF gene as a model of human deafness<\/h2>\n
\n

Kahland T, Lindenwald DL, Jeschke M, Kusch K, Tkachenko Eikel O, Uhl M, R\u00fcger N, Drummer C, Wolf B, Benseler F, Brose N, Behr R & Moser T
\nNature Communications, March 2026<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

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\n 4. March 2026<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

OTOF Gene Therapy: From Breakthroughs to Roadmaps<\/h2>\n
\n

Wang Q, Moser T, Petit C, MedComm March 2026.<\/p>\n

In a recent study published in Nature Medicine, adeno-associated virus (AAV)-mediated OTOF gene replacement in autosomal recessive nonsyndromic deafness form 9 (DFNB9) patients restored near-physiological hearing and markedly improved speech perception [1]. These results move otoferlin therapy from preclinical promise to a realistic, early-life precision treatment, positioning OTOF as a pathfinder for broader genetic cures for hereditary deafness and motivating scalable trial, manufacturing, and regulatory roadmaps. <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n <\/div>[\/vc_column_text][vc_empty_space height=”80px”][vc_column_text]\n

2025<\/span><\/h2>\n[\/vc_column_text][vc_column_text]
\n
\n 15. December 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities<\/h2>\n
\n

Optogenetics allows versatile control of excitable cell networks, which advances basic science research and drives the development of future medical applications. Fast-closing channelrhodopsins (ChRs) are required for high temporal fidelity of neurostimulation, but their short channel open times require sufficient plasma membrane expression and high light intensity, challenging clinical translation.<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 12. November 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins with Light<\/h2>\n
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Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light (2025) Zipf D, Vogt M, Sathyanarayanan U, Wagdi A, Riebeling J, Patejdl R, Bruegmann T. Neurogastroenterol Motil.<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 11. November 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

International Expert Consensus on Gene Therapy for Hereditary Hearing Loss: Based on Clinical Trials<\/h2>\n
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International Expert Consensus on Gene Therapy for Hereditary Hearing Loss: Based on Clinical Trials (2025) Fan X, Gao Z, Zhong J, Chen Y, Chen X, Landegger LD, Moser T, Zeng FG, Sun Y, Jin X, Nash R, Chien WW, Jiang D, Greinwald JH, Bance M, Rodr\u00edguez MM, Lee SY, Feng G, Yang H, Wu CC, Xu L, Yuan W, Feng Y, Zhao Y, Vona BC, Strenzke N, Beutner D, Amin N, Arwyn-Jones J, Chandrasekeharan D, Shi D, Zhang D, Yang J, Qi J, Wang Q, Yin Y, Cheng YF, Tao Y, Yu Y, Wang D, Jiang L, Guo L, Chen L, Cheng X, Cui C, Lv J, Han S, Wang W, Li Y, Gao X, Liu XZ, Zha D, Shi H, Chen B, Wang Q, Yuan H, Yang S, Yin S, Wu H, Wang Z, Li H, Rubinstein JT, Lustig LR, Chai R, Chen ZY, Shu Y. Med. 2025 Oct 23:100886<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

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\n 10. November 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Charting the Nanotopography of Inner Hair Cell Synapses Using MINFLUX Nanoscopy<\/h2>\n
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Charting the nanotopography of inner hair cell synapses using MINFLUX nanoscopy (2025) Rohan Kapoor, Hyojin Kim, Evelyn Garlick, Maria Augusta do R. B. F. Lima, Klara Esch, Torben Ruhwedel, Wiebke M\u00f6bius, Fred Wolf, Tobias Moser. Science Advances <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

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\n 16. September 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Isotropic, Aberration-Corrected Light Sheet Microscopy for Rapid High-Resolution Imaging of Cleared Tissue<\/h2>\n
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Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue (2025) Aakhte M, M\u00fcller GF, Roos L, Li J, G\u00f6pel T, Weiss K, Meric A, Wenzel J, Schwaninger M, Moser T, Huisken J. Nat Biotechnol. 2025, accepted <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 11. September 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Visual objects refine head direction coding<\/h2>\n
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Visual objects refine head direction coding (2025) Dominique Siegenthaler, Henry Denny, Sof\u00eda Skromne Carrasco,\u00a0<\/sup>Johanna Luise Mayer, Daniel Levenstein, Adrien Peyrache, Stuart Trenholm und Emilie Mac\u00e9.\u00a0Science<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 9. September 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Is CABP2-Associated Hearing Loss (DFNB93) a Gene Therapy Target? Preclinical Progress and Patient Registry<\/h2>\n
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Is CABP2-Associated Hearing Loss (DFNB93) a Gene Therapy Target? (2025) Barbara Vona, Bernd Wollnik, Nicola Strenzke, Tina Pangr\u0161i\u010d, Tobias Moser. Preclinical Progress and Patient Registry.<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 15. August 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Gastric Pacemaker Update: Relevance for Gastroparesis<\/h2>\n
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Gastric Pacemaker Update: Relevance for Gastroparesis (2025) Riebeling J, Patejdl R, Zipf D, Conradi LC, Ghadimi M, Gundling F, Bruegmann T., Zentralbl Chir. 337-345. [Update on Gastric Pacemaking: Relevance for Gastroparesis]\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 28. July 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Efficient and Sustained Optogenetic Control of Sensory and Cardiac Systems<\/h2>\n
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Efficient and sustained optogenetic control of sensory and cardiac systems (2025) Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hu\u0308ser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband M, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Mac\u00e9 E, Kusch K, Bruegmann T, Wolf BJ, Mager T, Moser T. Nat Biomed Engin.<\/p>\n <\/div>\n <\/div>\n

\n
\n 10. June 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Toward Elucidating the Mechanism of Cochlear Stimulation by Infrared Light<\/h2>\n
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Toward elucidating the mechanism of cochlear stimulation by infrared light (2025) Moser T. and Roos L. Proc Natl Acad Sci U S A; 122 (22):e2507582122<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 18. March 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

Improved Optogenetic Modification of Spiral Ganglion Neurons for Future Optical Cochlear Implants<\/h2>\n
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Improved optogenetic modification of spiral ganglion neurons for future optical cochlear implants (2025) Thirumalai A, Henseler J, Enayati M, Kusch K, Hessler R, Moser T, Huet AT. Theranostics 15(10):4270-4286. <\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n

\n
\n 18. March 2025<\/span>\n | <\/span>\n Publikation<\/span>\n <\/div>\n

CryoRhodopsins: a Comprehensive Characterization of a Group of Microbial Rhodopsins from Cold Environments<\/h2>\n
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CryoRhodopsins: a comprehensive characterization of a group of microbial rhodopsins from cold environments (2025) Lamm GHU, Marin E, Alekseev A, Schellbach AV, Stetsenko A, Haro-Moreno JM, Bourenkov G, Borshchevskiy V, Asido M, Agthe M, Engilberge S, Rose SL, Caramello N, Royant A, Schneider TR, Bateman A, Mager T, Moser T, Roriguez-Valera F, Wachtveitl J, Guskov A, Kovalev K. Sci Adv.ances,Vol 11, <\/span>Issue 27.<\/p>\n <\/div>\n \n\ud83d\udd17<\/span> Read Article <\/a>\n <\/div>\n <\/div>[\/vc_column_text][vc_empty_space height=”100px”][vc_separator border_width=”2″][\/vc_column][\/vc_row][\/vc_section][vc_section][vc_row row_type=”main-section” stukram_section_layout=”section_grid”][vc_column][vc_empty_space height=”100px”][vc_column_text]\n

2024<\/span><\/h2>\n[\/vc_column_text][vc_column_text]

Keine Publikationen gefunden.<\/p>[\/vc_column_text][\/vc_column][\/vc_row][\/vc_section]\n<\/div>","protected":false},"excerpt":{"rendered":"

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